Nucleolin Rescues TDP-43 Toxicity in Yeast and Human Cell Models

TDP-43 is a nuclear protein involved in pivotal processes, extensively studied for its implication in neurodegenerative disorders. TDP-43 cytosolic inclusions are a common neuropathologic hallmark in amyotrophic lateral sclerosis (ALS) and related diseases, and it is now established that TDP-43 misf...

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Bibliografski detalji
Izdano u:Front Cell Neurosci
Glavni autori: Peggion, Caterina, Massimino, Maria Lina, Stella, Roberto, Bortolotto, Raissa, Agostini, Jessica, Maldi, Arianna, Sartori, Geppo, Tonello, Fiorella, Bertoli, Alessandro, Lopreiato, Raffaele
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072491/
https://ncbi.nlm.nih.gov/pubmed/33912014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.625665
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