Nucleolin Rescues TDP-43 Toxicity in Yeast and Human Cell Models

TDP-43 is a nuclear protein involved in pivotal processes, extensively studied for its implication in neurodegenerative disorders. TDP-43 cytosolic inclusions are a common neuropathologic hallmark in amyotrophic lateral sclerosis (ALS) and related diseases, and it is now established that TDP-43 misf...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Peggion, Caterina, Massimino, Maria Lina, Stella, Roberto, Bortolotto, Raissa, Agostini, Jessica, Maldi, Arianna, Sartori, Geppo, Tonello, Fiorella, Bertoli, Alessandro, Lopreiato, Raffaele
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072491/
https://ncbi.nlm.nih.gov/pubmed/33912014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.625665
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