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The impact of identity by descent on fitness and disease in dogs

Domestic dogs have experienced population bottlenecks, recent inbreeding, and strong artificial selection. These processes have simplified the genetic architecture of complex traits, allowed deleterious variation to persist, and increased both identity-by-descent (IBD) segments and runs of homozygos...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Mooney, Jazlyn A., Yohannes, Abigail, Lohmueller, Kirk E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072400/
https://ncbi.nlm.nih.gov/pubmed/33853941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019116118
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