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The impact of identity by descent on fitness and disease in dogs
Domestic dogs have experienced population bottlenecks, recent inbreeding, and strong artificial selection. These processes have simplified the genetic architecture of complex traits, allowed deleterious variation to persist, and increased both identity-by-descent (IBD) segments and runs of homozygos...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8072400/ https://ncbi.nlm.nih.gov/pubmed/33853941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019116118 |
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