Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma

Primary Open Angle Glaucoma (POAG) is the most common form of glaucoma that leads to irreversible vision loss. Dysfunction of trabecular meshwork (TM) tissue, a major regulator of aqueous humor (AH) outflow resistance, is associated with intraocular pressure (IOP) elevation in POAG. However, the und...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Patel, Pinkal D., Chen, Yen-Lin, Kasetti, Ramesh B., Maddineni, Prabhavathi, Mayhew, William, Millar, J. Cameron, Ellis, Dorette Z., Sonkusare, Swapnil K., Zode, Gulab S.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072326/
https://ncbi.nlm.nih.gov/pubmed/33853948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2022461118
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