Aberrant Gut Microbiome Contributes to Intestinal Oxidative Stress, Barrier Dysfunction, Inflammation and Systemic Autoimmune Responses in MRL/lpr Mice

Microbiome composition and function have been implicated as contributing factors in the pathogenesis of autoimmune diseases (ADs), including systemic lupus erythematosus (SLE), rheumatoid arthritis and autoimmune hepatitis (AIH). Furthermore, dysbiosis of gut microbiome is associated with impaired b...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Wang, Hui, Wang, Gangduo, Banerjee, Nivedita, Liang, Yuejin, Du, Xiaotang, Boor, Paul J., Hoffman, Kristi L., Khan, M. Firoze
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071869/
https://ncbi.nlm.nih.gov/pubmed/33912174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.651191
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