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Differential oxidative modification of proteins in MRL+/+and MRL/lpr mice: Increased formation of lipid peroxidation-derived aldehyde-protein adducts may contribute to accelerated onset of autoimmune response

Even though reactive oxygen species (ROS) have been implicated in SLE pathogenesis, the contributory role of ROS, especially the consequences of oxidative modification of proteins by lipid peroxidation-derived aldehydes (LPDAs) such as malondialdehyde (MDA) and 4-hydroxynonenal (HNE) in eliciting an...

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Detalhes bibliográficos
Publicado no:Free Radic Res
Main Authors: Wang, Gangduo, Li, Hui, Khan, M. Firoze
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433085/
https://ncbi.nlm.nih.gov/pubmed/22950782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2012.727209
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