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Differential oxidative modification of proteins in MRL+/+and MRL/lpr mice: Increased formation of lipid peroxidation-derived aldehyde-protein adducts may contribute to accelerated onset of autoimmune response

Even though reactive oxygen species (ROS) have been implicated in SLE pathogenesis, the contributory role of ROS, especially the consequences of oxidative modification of proteins by lipid peroxidation-derived aldehydes (LPDAs) such as malondialdehyde (MDA) and 4-hydroxynonenal (HNE) in eliciting an...

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Pubblicato in:Free Radic Res
Autori principali: Wang, Gangduo, Li, Hui, Khan, M. Firoze
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433085/
https://ncbi.nlm.nih.gov/pubmed/22950782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2012.727209
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