Aberrant Gut Microbiome Contributes to Intestinal Oxidative Stress, Barrier Dysfunction, Inflammation and Systemic Autoimmune Responses in MRL/lpr Mice

Microbiome composition and function have been implicated as contributing factors in the pathogenesis of autoimmune diseases (ADs), including systemic lupus erythematosus (SLE), rheumatoid arthritis and autoimmune hepatitis (AIH). Furthermore, dysbiosis of gut microbiome is associated with impaired b...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Wang, Hui, Wang, Gangduo, Banerjee, Nivedita, Liang, Yuejin, Du, Xiaotang, Boor, Paul J., Hoffman, Kristi L., Khan, M. Firoze
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071869/
https://ncbi.nlm.nih.gov/pubmed/33912174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.651191
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