Population Pharmacokinetics and Safety of Oral Tetra-Arsenic Tetra-Sulfide Formula in Pediatric Acute Promyelocytic Leukemia

BACKGROUND: An oral tetra-arsenic tetra-sulfide (AS(4)S(4)) formula has been recommended as an outpatient post-remission treatment for Chinese adults with acute promyelocytic leukemia (APL) but limited data are available for children. In this exploratory study, we aimed to evaluate the pharmacokinet...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Zhang, Li, Yang, Xin-Mei, Chen, Jing, Hu, Lei, Yang, Fan, Zhou, Yue, Zhao, Bei-Bei, Zhao, Wei, Zhu, Xiao-Fan
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2021
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071704/
https://ncbi.nlm.nih.gov/pubmed/33911851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S305244
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