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The Alteration of L-Carnitine Transport and Pretreatment Effect under Glutamate Cytotoxicity on Motor Neuron-Like NSC-34 Lines

L-Carnitine (LC) is essential for transporting fatty acids to the mitochondria for β-oxidation. This study was performed to examine the alteration of the LC transport system in wild type (WT, NSC-34/hSOD1(WT)) and mutant type (MT, NSC-34/hSOD1(G93A)) amyotrophic lateral sclerosis (ALS) models. The u...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Gyawali, Asmita, Hyeon, Seung Jae, Ryu, Hoon, Kang, Young-Sook
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070968/
https://ncbi.nlm.nih.gov/pubmed/33919926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040551
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