Role of Electrostatic Interactions in Calcitonin Prefibrillar Oligomer-Induced Amyloid Neurotoxicity and Protective Effect of Neuraminidase

Salmon calcitonin is a good model for studying amyloid behavior and neurotoxicity. Its slow aggregation rate allows the purification of low molecular weight prefibrillar oligomers, which are the most toxic species. It has been proposed that these species may cause amyloid pore formation in neuronal...

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Publicado en:Int J Mol Sci
Autores principales: Cariati, Ida, Bonanni, Roberto, Marini, Mario, Rinaldi, Anna Maria, Zarrilli, Beatrice, Tancredi, Virginia, Frank, Claudio, D’Arcangelo, Giovanna, Diociaiuti, Marco
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8070249/
https://ncbi.nlm.nih.gov/pubmed/33920464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083947
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