The Interaction between Amyloid Prefibrillar Oligomers of Salmon Calcitonin and a Lipid-Raft Model: Molecular Mechanisms Leading to Membrane Damage, Ca(2+)-Influx and Neurotoxicity

To investigate the interaction between amyloid assemblies and “lipid-rafts”, we performed functional and structural experiments on salmon calcitonin (sCT) solutions rich in prefibrillar oligomers, proto- and mature-fibers interacting with liposomes made of monosialoganglioside-GM1 (4%), DPPC (48%) a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Diociaiuti, Marco, Bombelli, Cecilia, Zanetti-Polzi, Laura, Belfiore, Marcello, Fioravanti, Raoul, Macchia, Gianfranco, Giordani, Cristiano
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7022306/
https://ncbi.nlm.nih.gov/pubmed/31905804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10010058
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados