Clinically Relevant Concentrations of Polymyxin B and Meropenem Synergistically Kill Multidrug-Resistant Pseudomonas aeruginosa and Minimize Biofilm Formation

The emergence of antibiotic resistance has severely impaired the treatment of chronic respiratory infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa. Since the reintroduction of polymyxins as a last-line therapy against MDR Gram-negative bacteria, resistance to its monotherapy and...

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Détails bibliographiques
Publié dans:Antibiotics (Basel)
Auteurs principaux: Wickremasinghe, Hasini, Yu, Heidi H., Azad, Mohammad A. K., Zhao, Jinxin, Bergen, Phillip J., Velkov, Tony, Zhou, Qi Tony, Zhu, Yan, Li, Jian
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069709/
https://ncbi.nlm.nih.gov/pubmed/33918040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics10040405
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