Synergistic Killing of Polymyxin B in Combination With the Antineoplastic Drug Mitotane Against Polymyxin-Susceptible and -Resistant Acinetobacter baumannii: A Metabolomic Study

Polymyxins are currently used as the last-resort antibiotics against multidrug-resistant Acinetobacter baumannii. As resistance to polymyxins emerges in A. baumannii with monotherapy, combination therapy is often the only remaining treatment option. A novel approach is to employ the combination of p...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Tran, Thien B., Bergen, Phillip J., Creek, Darren J., Velkov, Tony, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911485/
https://ncbi.nlm.nih.gov/pubmed/29713282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00359
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