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Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii

Combination therapy is deployed for the treatment of multidrug-resistant Acinetobacter baumannii, as it can rapidly develop resistance to current antibiotics. This is the first study to investigate the synergistic effect of colistin/doripenem combination on the metabolome of A. baumannii. The metabo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maifiah, Mohd Hafidz Mahamad, Creek, Darren J., Nation, Roger L., Forrest, Alan, Tsuji, Brian T., Velkov, Tony, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5371981/
https://ncbi.nlm.nih.gov/pubmed/28358014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45527
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