Comparative Metabolomics Reveals Key Pathways Associated With the Synergistic Killing of Colistin and Sulbactam Combination Against Multidrug-Resistant Acinetobacter baumannii

Background: Polymyxins are a last-line class of antibiotics against multidrug-resistant Acinetobacter baumannii. However, polymyxin resistance can emerge with monotherapy, highlighting the need for synergistic combination therapies. Polymyxins in combination with β-lactams have shown remarkable syne...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Han, Mei-Ling, Liu, Xiaofen, Velkov, Tony, Lin, Yu-Wei, Zhu, Yan, Creek, Darren J., Barlow, Christopher K., Yu, Heidi H., Zhou, Zhihui, Zhang, Jing, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620532/
https://ncbi.nlm.nih.gov/pubmed/31333468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00754
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