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Membrane Environment Modulates Ligand-Binding Propensity of P2Y12 Receptor

The binding of natural ligands and synthetic drugs to the P2Y12 receptor is of great interest because of its crucial role in platelets activation and the therapy of arterial thrombosis. Up to now, all computational studies of P2Y12 concentrated on the available crystal structures, while the role of...

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Detaylı Bibliyografya
Yayımlandı:Pharmaceutics
Asıl Yazarlar: Haghighi, Fatemeh, Yesylevskyy, Semen, Davani, Siamak, Ramseyer, Christophe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069422/
https://ncbi.nlm.nih.gov/pubmed/33918934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13040524
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