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The asymmetry of plasma membranes and their cholesterol content influence the uptake of cisplatin

The composition of the plasma membrane of malignant cells is thought to influence the cellular uptake of cisplatin and to take part in developing resistance to this widespread anti-cancer drug. In this work we study the permeation of cisplatin through the model membranes of normal and cancer cells u...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rivel, Timothée, Ramseyer, Christophe, Yesylevskyy, Semen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449338/
https://ncbi.nlm.nih.gov/pubmed/30948733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41903-w
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