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The asymmetry of plasma membranes and their cholesterol content influence the uptake of cisplatin

The composition of the plasma membrane of malignant cells is thought to influence the cellular uptake of cisplatin and to take part in developing resistance to this widespread anti-cancer drug. In this work we study the permeation of cisplatin through the model membranes of normal and cancer cells u...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Rivel, Timothée, Ramseyer, Christophe, Yesylevskyy, Semen
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449338/
https://ncbi.nlm.nih.gov/pubmed/30948733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41903-w
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