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The asymmetry of plasma membranes and their cholesterol content influence the uptake of cisplatin

The composition of the plasma membrane of malignant cells is thought to influence the cellular uptake of cisplatin and to take part in developing resistance to this widespread anti-cancer drug. In this work we study the permeation of cisplatin through the model membranes of normal and cancer cells u...

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Опубликовано в: :Sci Rep
Главные авторы: Rivel, Timothée, Ramseyer, Christophe, Yesylevskyy, Semen
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449338/
https://ncbi.nlm.nih.gov/pubmed/30948733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41903-w
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