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A Role for RAGE in DNA Double Strand Breaks (DSBs) Detected in Pathological Placentas and Trophoblast Cells

Impaired DNA damage responses are associated with several diseases, including pregnancy complications. Recent research identified an ATM-kinase dependent function for the nuclear isoform of the receptor for advanced glycation end-products (RAGE) during double strand break (DSB)-repair. RAGE contribu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Tsai, Kary Y.F., Tullis, Benton, Breithaupt, Katrina L., Fowers, Rylan, Jones, Nelson, Grajeda, Samuel, Reynolds, Paul R., Arroyo, Juan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069300/
https://ncbi.nlm.nih.gov/pubmed/33918759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040857
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