Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury

Peripheral nerve injury induces long-term pro-inflammatory responses in spinal cord glial cells that facilitate neuropathic pain, but the identity of endogenous cells that resolve spinal inflammation has not been determined. Guided by single-cell RNA-seq (scRNAseq), we found that MRC1(+) spinal cord...

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Bibliografske podrobnosti
izdano v:Neuron
Main Authors: Niehaus, Jesse K., Taylor-Blake, Bonnie, Loo, Lipin, Simon, Jeremy M., Zylka, Mark J.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8068642/
https://ncbi.nlm.nih.gov/pubmed/33667343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2021.02.018
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