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Acetyl-CoA Metabolism and Histone Acetylation in the Regulation of Aging and Lifespan
Acetyl-CoA is a metabolite at the crossroads of central metabolism and the substrate of histone acetyltransferases regulating gene expression. In many tissues fasting or lifespan extending calorie restriction (CR) decreases glucose-derived metabolic flux through ATP-citrate lyase (ACLY) to reduce cy...
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| Publicado no: | Antioxidants (Basel) |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8068152/ https://ncbi.nlm.nih.gov/pubmed/33917812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10040572 |
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