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Prevention of Bone Destruction by Mechanical Loading Is Not Enhanced by the Bruton’s Tyrosine Kinase Inhibitor CC-292 in Myeloma Bone Disease

Limiting bone resorption and regenerating bone tissue are treatment goals in myeloma bone disease (MMBD). Physical stimuli such as mechanical loading prevent bone destruction and enhance bone mass in the MOPC315.BM.Luc model of MMBD. It is unknown whether treatment with the Bruton’s tyrosine kinase...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ziouti, Fani, Rummler, Maximilian, Steyn, Beatrice, Thiele, Tobias, Seliger, Anne, Duda, Georg N., Bogen, Bjarne, Willie, Bettina M., Jundt, Franziska
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067978/
https://ncbi.nlm.nih.gov/pubmed/33917250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083840
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