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Prevention of Bone Destruction by Mechanical Loading Is Not Enhanced by the Bruton’s Tyrosine Kinase Inhibitor CC-292 in Myeloma Bone Disease

Limiting bone resorption and regenerating bone tissue are treatment goals in myeloma bone disease (MMBD). Physical stimuli such as mechanical loading prevent bone destruction and enhance bone mass in the MOPC315.BM.Luc model of MMBD. It is unknown whether treatment with the Bruton’s tyrosine kinase...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Ziouti, Fani, Rummler, Maximilian, Steyn, Beatrice, Thiele, Tobias, Seliger, Anne, Duda, Georg N., Bogen, Bjarne, Willie, Bettina M., Jundt, Franziska
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067978/
https://ncbi.nlm.nih.gov/pubmed/33917250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083840
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