NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Skeletal development and remodeling of adult bone are critically controlled by activated NOTCH signaling in genetically modified mice. It is yet unclear whether NOTCH signaling is activated by mechanical strain sensed by bone cells. We found that expression of specific NOTCH target genes is induced...

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Bibliografiska uppgifter
I publikationen:Stem Cells Int
Huvudupphovsmän: Ziouti, Fani, Ebert, Regina, Rummler, Maximilian, Krug, Melanie, Müller-Deubert, Sigrid, Lüdemann, Martin, Jakob, Franz, Willie, Bettina M., Jundt, Franziska
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413410/
https://ncbi.nlm.nih.gov/pubmed/30936923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5150634
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