NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Skeletal development and remodeling of adult bone are critically controlled by activated NOTCH signaling in genetically modified mice. It is yet unclear whether NOTCH signaling is activated by mechanical strain sensed by bone cells. We found that expression of specific NOTCH target genes is induced...

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Dettagli Bibliografici
Pubblicato in:Stem Cells Int
Autori principali: Ziouti, Fani, Ebert, Regina, Rummler, Maximilian, Krug, Melanie, Müller-Deubert, Sigrid, Lüdemann, Martin, Jakob, Franz, Willie, Bettina M., Jundt, Franziska
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413410/
https://ncbi.nlm.nih.gov/pubmed/30936923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5150634
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