NOTCH Signaling Is Activated through Mechanical Strain in Human Bone Marrow-Derived Mesenchymal Stromal Cells

Skeletal development and remodeling of adult bone are critically controlled by activated NOTCH signaling in genetically modified mice. It is yet unclear whether NOTCH signaling is activated by mechanical strain sensed by bone cells. We found that expression of specific NOTCH target genes is induced...

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Publicat a:Stem Cells Int
Autors principals: Ziouti, Fani, Ebert, Regina, Rummler, Maximilian, Krug, Melanie, Müller-Deubert, Sigrid, Lüdemann, Martin, Jakob, Franz, Willie, Bettina M., Jundt, Franziska
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413410/
https://ncbi.nlm.nih.gov/pubmed/30936923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5150634
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