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Comparing the immunosuppressive potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells

BACKGROUND: SB623 cells are expanded from marrow stromal cells (MSCs) transfected with a Notch intracellular domain (NICD)-expressing plasmid. In stroke-induced animals, these cells reduce infarct size and promote functional recovery. SB623 cells resemble the parental MSCs with respect to morphology...

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Detalhes bibliográficos
Main Authors: Dao, Mo A, Tate, Ciara C, Aizman, Irina, McGrogan, Michael, Case, Casey C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228829/
https://ncbi.nlm.nih.gov/pubmed/21982515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-133
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