Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells

Bone marrow-derived mesenchymal stromal cells (hMSCs) are capable of differentiating into the osteogenic lineage, and for osteogenic differentiation, mechanical loading is a relevant stimulus. Mechanotransduction leads to the formation of second messengers such as cAMP, cGMP, or Ca(2+) influx result...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Müller-Deubert, Sigrid, Ege, Carolin, Krug, Melanie, Meißner-Weigl, Jutta, Rudert, Maximilian, Bischof, Oliver, Jakob, Franz, Ebert, Regina
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294361/
https://ncbi.nlm.nih.gov/pubmed/32587621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7865484
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