Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells

Bone marrow-derived mesenchymal stromal cells (hMSCs) are capable of differentiating into the osteogenic lineage, and for osteogenic differentiation, mechanical loading is a relevant stimulus. Mechanotransduction leads to the formation of second messengers such as cAMP, cGMP, or Ca(2+) influx result...

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Bibliografski detalji
Izdano u:Stem Cells Int
Glavni autori: Müller-Deubert, Sigrid, Ege, Carolin, Krug, Melanie, Meißner-Weigl, Jutta, Rudert, Maximilian, Bischof, Oliver, Jakob, Franz, Ebert, Regina
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294361/
https://ncbi.nlm.nih.gov/pubmed/32587621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7865484
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