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Protein O-Fucosyltransferase 1 Undergoes Interdomain Flexibility in Solution

Protein O-fucosyltransferase 1 (PoFUT1) is a GT-B fold enzyme that fucosylates proteins containing EGF-like repeats. GT-B glycosyltransferases have shown a remarkable grade of plasticity adopting closed and open conformations as a way of tuning their catalytic cycle, a feature that has not been obse...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Lira-Navarrete, Erandi, Pallarés, María Carmen, Castello, Fabio, Ruedas-Rama, Maria J., Orte, Angel, Lostao, Anabel, Hurtado-Guerrero, Ramón
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8067585/
https://ncbi.nlm.nih.gov/pubmed/33916911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26082105
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