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Priming of the cGAS-STING-TBK1 Pathway Enhances LPS-Induced Release of Type I Interferons
Cytoplasmic nucleic acids sensing through cGAS-STING-TBK1 pathway is crucial for the production of antiviral interferons (IFNs). IFN production can also be induced by lipopolysaccharide (LPS) stimulation through Toll-like receptor 4 (TLR4) in appropriate conditions. Of note, both IFN production and...
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| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8067196/ https://ncbi.nlm.nih.gov/pubmed/33916318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040785 |
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