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LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss

Senescence of bone marrow-derived mesenchymal stem cells (BMSCs) has been widely reported to be closely correlated with aging-related diseases, including osteoporosis (OP). Moreover, the beneficial functions of BMSCs decline with age, limiting their therapeutic efficacy in OP. In the present study,...

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書目詳細資料
發表在:	Redox Biol
Main Authors:	Liu, Fei, Yuan, Yujia, Bai, Lin, Yuan, Longhui, Li, Lan, Liu, Jingping, Chen, Younan, Lu, Yanrong, Cheng, Jingqiu, Zhang, Jie
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2021
主題:	Research Paper
在線閱讀:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8066428/ https://ncbi.nlm.nih.gov/pubmed/33865167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.101963
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LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss

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