Activation of TFEB-mediated autophagy by trehalose attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury

Aims: Cisplatin, an anticancer drug, always leads to nephrotoxicity by causing mitochondrial dysfunction. As a major mechanism for cellular self-degradation, autophagy has been proven to protect against cisplatin-induced acute kidney injury (AKI). Based on the activation of autophagy induced by treh...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhu, Lingling, Yuan, Yujia, Yuan, Longhui, Li, Lan, Liu, Fei, Liu, Jingping, Chen, Younan, Lu, Yanrong, Cheng, Jingqiu
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255003/
https://ncbi.nlm.nih.gov/pubmed/32483422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.44051
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