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Involvement of Local, Rapid Conformational Dynamics in Binding of Flexible Recognition Motifs

Flexible protein sequences populate ensembles of rapidly interconverting states differentiated by small-scale fluctuations; however, elucidating whether and how the ensembles determine function experimentally is challenged by the combined high spatial and temporal resolution needed to capture the st...

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Vydáno v:J Phys Chem B
Hlavní autoři: Bukowski, Gregory S., Horness, Rachel E., Thielges, Megan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066399/
https://ncbi.nlm.nih.gov/pubmed/31535866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.9b07036
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