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Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition

Antibody–antigen interactions are governed by recognition of specific residues and structural complementarity between the antigen epitope and antibody paratope. While X-ray crystallography has provided detailed insights into static conformations of antibody–antigen complexes, factors such as conform...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Liang, Yu, Guttman, Miklos, Davenport, Thaddeus M., Hu, Shiu-Lok, Lee, Kelly K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479570/
https://ncbi.nlm.nih.gov/pubmed/27003615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01354
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