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Molecular Dynamics Study of the Changes in Conformation of Calmodulin with Calcium Binding and/or Target Recognition

Calmodulin is a calcium binding protein with two lobes, N-lobe and C-lobe, which evolved from duplication and fusion of a single precursor lobe of a pair of EF-hand. These two lobes of calmodulin show subtle differences in calcium binding and target recognition; these are important for the functions...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kawasaki, Hiroshi, Soma, Natsumi, Kretsinger, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650393/
https://ncbi.nlm.nih.gov/pubmed/31337841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47063-1
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