Wird geladen...

Impaired Mitochondrial Function in iPSC-Retinal Pigment Epithelium with the Complement Factor H Polymorphism for Age-Related Macular Degeneration

Age-related macular degeneration (AMD), the leading cause of vision loss in the elderly, is characterized by loss of the retinal pigment epithelium (RPE). While the disease mechanism remains unclear, prior studies have linked AMD with RPE mitochondrial defects and genetic polymorphisms in the comple...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Ebeling, Mara C., Geng, Zhaohui, Kapphahn, Rebecca J., Roehrich, Heidi, Montezuma, Sandra R., Dutton, James R., Ferrington, Deborah A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8066149/
https://ncbi.nlm.nih.gov/pubmed/33918210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10040789
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!