Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness among older adults. It has been suggested that mitochondrial defects in the retinal pigment epithelium (RPE) underlies AMD pathology. To test this idea, we developed primary cultures of RPE to ask whether RPE from donors with A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Redox Biol
Prif Awduron: Ferrington, Deborah A., Ebeling, Mara C., Kapphahn, Rebecca J., Terluk, Marcia R., Fisher, Cody R., Polanco, Jorge R., Roehrich, Heidi, Leary, Michaela M., Geng, Zhaohui, Dutton, James R., Montezuma, Sandra R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466586/
https://ncbi.nlm.nih.gov/pubmed/28600982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.05.015
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