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Interaction of Ligands for PET with the Dopamine D3 Receptor: In Silico and In Vitro Methods

[(18)F]Fallypride and [(18)F]Fluortriopride (FTP) are two different PET radiotracers that bind with sub-nanomolar affinity to the dopamine D3 receptor (D(3)R). In spite of their similar D(3) affinities, the two PET ligands display very different properties for labeling the D(3)R in vivo: [(18)F]Fall...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Hsieh, Chia-Ju, Riad, Aladdin, Lee, Ji Youn, Sahlholm, Kristoffer, Xu, Kuiying, Luedtke, Robert R., Mach, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065765/
https://ncbi.nlm.nih.gov/pubmed/33918451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11040529
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