Disrupting Reconsolidation by Systemic Inhibition of mTOR Kinase via Rapamycin Reduces Cocaine-Seeking Behavior

Drug addiction is considered maladaptive learning, and drug-related memories aroused by the presence of drug related stimuli (drug context or drug-associated cues) promote recurring craving and reinstatement of drug seeking. The mammalian target of rapamycin signaling pathway is involved in reconsol...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhang, Fushen, Huang, Shihao, Bu, Haiyan, Zhou, Yu, Chen, Lixiang, Kang, Ziliu, Chen, Liangpei, Yan, He, Yang, Chang, Yan, Jie, Jian, Xiaohong, Luo, Yixiao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064688/
https://ncbi.nlm.nih.gov/pubmed/33897438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.652865
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