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Hydraulic resistance induces cell phenotypic transition in confinement

Cells penetrating into confinement undergo mesenchymal-to-amoeboid transition. The topographical features of the microenvironment expose cells to different hydraulic resistance levels. How cells respond to hydraulic resistance is unknown. We show that the cell phenotype shifts from amoeboid to mesen...

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Bibliografische gegevens
Gepubliceerd in:Sci Adv
Hoofdauteurs: Zhao, Runchen, Cui, Siqi, Ge, Zhuoxu, Zhang, Yuqi, Bera, Kaustav, Zhu, Lily, Sun, Sean X., Konstantopoulos, Konstantinos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064631/
https://ncbi.nlm.nih.gov/pubmed/33893091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg4934
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