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Hydraulic resistance induces cell phenotypic transition in confinement

Cells penetrating into confinement undergo mesenchymal-to-amoeboid transition. The topographical features of the microenvironment expose cells to different hydraulic resistance levels. How cells respond to hydraulic resistance is unknown. We show that the cell phenotype shifts from amoeboid to mesen...

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Bibliografski detalji
Izdano u:Sci Adv
Glavni autori: Zhao, Runchen, Cui, Siqi, Ge, Zhuoxu, Zhang, Yuqi, Bera, Kaustav, Zhu, Lily, Sun, Sean X., Konstantopoulos, Konstantinos
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064631/
https://ncbi.nlm.nih.gov/pubmed/33893091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg4934
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