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Hydraulic resistance induces cell phenotypic transition in confinement

Cells penetrating into confinement undergo mesenchymal-to-amoeboid transition. The topographical features of the microenvironment expose cells to different hydraulic resistance levels. How cells respond to hydraulic resistance is unknown. We show that the cell phenotype shifts from amoeboid to mesen...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Zhao, Runchen, Cui, Siqi, Ge, Zhuoxu, Zhang, Yuqi, Bera, Kaustav, Zhu, Lily, Sun, Sean X., Konstantopoulos, Konstantinos
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064631/
https://ncbi.nlm.nih.gov/pubmed/33893091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg4934
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