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DNASE1L3 arrests tumor angiogenesis by impairing the senescence-associated secretory phenotype in response to stress

Hepatocellular carcinoma (HCC) is one of the most challenging and aggressive cancers with limited treatment options because of tumor heterogeneity. Tumor angiogenesis is a hallmark of HCC and is necessary for tumor growth and progression. DNA damage stress and its associated deoxyribonuclease1-like...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Guo, Deliang, Ma, Dong, Liu, Pengpeng, Lan, Jianwei, Liu, Zhisu, Liu, Quanyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064203/
https://ncbi.nlm.nih.gov/pubmed/33744849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202740
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