Dual activation of Hedgehog and Wnt/β-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer

Mounting evidence has shown that miRNA-150 expression is upregulated in gastric cancer (GC) and is associated with gastric carcinogenesis, but the underlying oncogenic mechanism remains elusive. Here, we discovered that miRNA-150 targets the tumor suppressor SUFU to promote cell proliferation, migra...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Peng, Yin, Zhang, Xiaojing, Lin, Huijuan, Deng, Shiqi, Qin, Ying, He, Jieqiong, Hu, Fan, Zhu, Xiaohui, Feng, Xianling, Wang, Jian, Wei, Yanjie, Fan, Xinmin, Lin, Huan, Ashktorab, Hassan, Smoot, Duane, Lv, Yansi, Li, Song, Meltzer, Stephen J., Jin, Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8064165/
https://ncbi.nlm.nih.gov/pubmed/33848981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202895
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