Loading...
A mid-throughput HBV replication inhibition assay capable of detecting ribonuclease H inhibitors
The hepatitis B virus (HBV) ribonuclease H (RNaseH) is a promising but unexploited drug target. Inhibiting the RNaseH blocks viral reverse transcription by truncating the minus-polarity DNA strand, causing accumulation of RNA:DNA heteroduplexes, and abrogating plus-polarity DNA synthesis. Screening...
Na minha lista:
| Udgivet i: | J Virol Methods |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8063683/ https://ncbi.nlm.nih.gov/pubmed/33766659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2021.114127 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|