Hydropathicity-based prediction of pain-causing NaV1.7 variants

BACKGROUND: Mutation-induced variations in the functional architecture of the NaV1.7 channel protein are causally related to a broad spectrum of human pain disorders. Predicting in silico the phenotype of NaV1.7 variant is of major clinical importance; it can aid in reducing costs of in vitro pathop...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Xenakis, Makros N., Kapetis, Dimos, Yang, Yang, Gerrits, Monique M., Heijman, Jordi, Waxman, Stephen G., Lauria, Giuseppe, Faber, Catharina G., Westra, Ronald L., Lindsey, Patrick J., Smeets, Hubert J.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063372/
https://ncbi.nlm.nih.gov/pubmed/33892629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-021-04119-2
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