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Impaired Suppression of Glucagon in Obese Subjects Parallels Decline in Insulin Sensitivity and Beta-Cell Function

AIM: To examine the relationship between plasma glucagon levels and insulin sensitivity and insulin secretion in obese subjects. METHODS: Suppression of plasma glucagon was examined in 275 obese Hispanic Americans with varying glucose tolerance. All subjects received a 2-hour oral glucose tolerance...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Endocrinol Metab
Hauptverfasser: Chen, Xi, Maldonado, Enrique, DeFronzo, Ralph A, Tripathy, Devjit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8063259/
https://ncbi.nlm.nih.gov/pubmed/33524152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgab019
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