Effect of Mild Physiologic Hyperglycemia on Insulin Secretion, Insulin Clearance, and Insulin Sensitivity in Healthy Glucose-Tolerant Subjects

The aim of the current study was to evaluate the effect of sustained physiologic increase of ∼50 mg/dL in plasma glucose concentration on insulin secretion in normal glucose-tolerant (NGT) subjects. Twelve NGT subjects without family history of type 2 diabetes mellitus (T2DM; FH−) and 8 NGT with fam...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Merovci, Aurora, Tripathy, Devjit, Chen, Xi, Valdez, Ivan, Abdul-Ghani, Muhammad, Solis-Herrera, Carolina, Gastaldelli, Amalia, DeFronzo, Ralph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2021
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881846/
https://ncbi.nlm.nih.gov/pubmed/33033064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db20-0039
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