Glucose homeostasis during prolonged suppression of glucagon and insulin secretion by somatostatin.

Somatostatin was infused for 5-8 hr into five normal men and eleven normal, conscious dogs. This infusion resulted in a persistent decline in plasma glucagon (40-60%) and insulin (30-45%). Plasma gluccose fell 15-25% during the initial 1-2 hr, but subsequently rose to hyperglycemic levels (130-155 m...

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Bibliographic Details
Main Authors: Sherwin, R S, Hendler, R, DeFronzo, R, Wahren, J, Felic, P
Format: Artigo
Language:Inglês
Published: 1977
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC393257/
https://ncbi.nlm.nih.gov/pubmed/264686
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