Glucose homeostasis during prolonged suppression of glucagon and insulin secretion by somatostatin.

Somatostatin was infused for 5-8 hr into five normal men and eleven normal, conscious dogs. This infusion resulted in a persistent decline in plasma glucagon (40-60%) and insulin (30-45%). Plasma gluccose fell 15-25% during the initial 1-2 hr, but subsequently rose to hyperglycemic levels (130-155 m...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Sherwin, R S, Hendler, R, DeFronzo, R, Wahren, J, Felic, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1977
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393257/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/264686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.1.348
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