Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development

Osteoarthritis (OA) is a degenerative joint disease with multiple etiologies that affects individuals worldwide. No effective interventions are currently available to reverse the pathological process of OA. Sodium butyrate (NaB), a component of short-chain fatty acids (SCFAs), has multiple biologica...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Zhou, Haikang, Li, Guoqing, Wang, Yang, Jiang, Rendong, Li, Yicheng, Wang, Huhu, Wang, Fei, Ma, Hairong, Cao, Li
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062861/
https://ncbi.nlm.nih.gov/pubmed/33897442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.659597
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