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Machine learning guided aptamer refinement and discovery
Aptamers are single-stranded nucleic acid ligands that bind to target molecules with high affinity and specificity. They are typically discovered by searching large libraries for sequences with desirable binding properties. These libraries, however, are practically constrained to a fraction of the t...
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| Gepubliceerd in: | Nat Commun |
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| Hoofdauteurs: | , , , , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8062585/ https://ncbi.nlm.nih.gov/pubmed/33888692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22555-9 |
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